In the pathophysiology of benign prostatic hyperplasia, which of the following enzymes is primarily responsible for the conversion of testosterone to dihydrotestosterone (DHT), the hormone responsible for prostatic growth?
Group of answer choices
- Acrosin
- 5-alpha reductase
- Aromatase
- 21-hydroxylase
The correct answer is: 5-alpha reductase
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Explanation:
5-alpha reductase is the enzyme responsible for converting testosterone into dihydrotestosterone (DHT), a more potent androgen that plays a key role in prostatic growth and the development of benign prostatic hyperplasia (BPH).
