NURS 6501: Final Exam Question 9 / NURS-6501N Advanced Pathophysiology

A patient presents with clusters of painful vesicles on the genitalia. Laboratory tests confirm the presence of a viral infection. What type of virus is responsible for these symptoms?

Group of answer choices

  • Retrovirus
  • Double-stranded DNA virus
  • Double-stranded RNA virus
  • Single-stranded RNA virus

The correct answer is: Double-stranded DNA virus

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Explanation:

The clinical presentation of painful genital vesicles is classic for herpes simplex virus (HSV) infection, most commonly HSV-2 (though HSV-1 can also cause genital herpes).

Key Features of HSV:

  • Virus type: HSV is a double-stranded DNA virus (family Herpesviridae).
  • Transmission: Sexual contact or direct mucosal/skin exposure.
  • Symptoms:
    • Clusters of painful vesicles that ulcerate and crust over.
    • May include prodromal tingling, itching, or burning.
    • Recurrent outbreaks possible due to viral latency in nerve ganglia.

Why Not the Others?

  • Retrovirus (e.g., HIV): Causes systemic immunosuppression, not localized vesicular lesions.
  • Double-stranded RNA virus (e.g., rotavirus): Primarily causes gastroenteritis.
  • Single-stranded RNA virus (e.g., HCV, influenza): Not associated with genital vesicular rashes.

Thus, HSV (a double-stranded DNA virus) is the causative agent.

 

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