NURS 6501: Final Exam Question 36 / NURS-6501N Advanced Pathophysiology

 

 

What is the key feature that differentiates a transient ischemic attack (TIA) from a stroke?

Group of answer choices

  • TIAs involve permanent brain injury.
  • TIAs usually last more than one hour.
  • TIAs are caused by bleeding in the brain.
  • TIAs usually resolve within a short period without infarction.

 

The correct answer is:

TIAs usually resolve within a short period without infarction.

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Explanation:

The key distinction between a transient ischemic attack (TIA) and a stroke is the absence of permanent brain damage (infarction) in TIA:

  • TIA:
    • Neurologic deficits resolve completely (typically within <1 hour, though by definition <24 hours).
    • No acute infarction on imaging (diffusion-weighted MRI is the gold standard to rule out small infarcts).
  • Stroke:
    • Permanent infarction occurs (visible on imaging).
    • Symptoms persist beyond 24 hours (though most strokes are evident much sooner).

Why Not the Others?

  • “TIAs involve permanent brain injury”: False—this defines a stroke, not a TIA.
  • “TIAs usually last >1 hour”: False—most resolve within 60 minutes (though the formal cutoff is 24h).
  • “TIAs are caused by bleeding”: False—TIAs are ischemic (due to temporary clot/hypoperfusion); bleeding causes hemorrhagic stroke.

Clinical Implications:

  • TIA is a medical emergency10-15% risk of stroke within 90 days (highest in first 48h).
  • ABCD2 score helps stratify risk and guide urgent evaluation (e.g., carotid imaging, anticoagulation for AF).

Thus, the transient nature without infarction is the defining feature of TIA.

 

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