What is the role of cytochrome C in cellular injury?
Group of answer choices
- Cytochrome C promotes the production of reactive oxygen species.
- Cytochrome C is released into the cytoplasm to enhance cellular repair mechanisms.
- Cytochrome C promotes apoptosome formation and apoptosis.
- Cytochrome C interacts with mitochondrial DNA to mitigate damage during injury.
The correct answer is: Cytochrome C promotes apoptosome formation and apoptosis.
Please contact distinguished papers for help with NURS 6501: Week 6 Midterm Exam / NURS-6501N Advanced Pathophysiology or any other assignment.
Email: distinguishedpapers@yahoo.com
Explanation:
- Cytochrome C promotes apoptosome formation and apoptosis: Cytochrome C is a key protein located in the mitochondria. During cellular stress or damage, it is released into the cytoplasm, where it interacts with other proteins (such as Apaf-1) to form the apoptosome. This complex activates caspases, which are enzymes responsible for carrying out the apoptotic process (programmed cell death).
Other options:
- Cytochrome C promotes the production of reactive oxygen species: While mitochondria are involved in generating reactive oxygen species (ROS), cytochrome C itself is not directly responsible for their production. ROS generation is more closely related to mitochondrial dysfunction or oxidative stress, not cytochrome C’s role in apoptosis.
- Cytochrome C is released into the cytoplasm to enhance cellular repair mechanisms: Cytochrome C’s release is associated with apoptosis, not repair mechanisms. Its release triggers cell death, not repair processes.
- Cytochrome C interacts with mitochondrial DNA to mitigate damage during injury: Cytochrome C does not interact with mitochondrial DNA to mitigate damage. Its main function in cellular injury is to initiate apoptosis when cellular damage is beyond repair.
Therefore, Cytochrome C promotes apoptosome formation and apoptosis is the correct choice.
